izindaba

Ngomhla ziyisi-8 kuMfumfu, ithimba labacwaningi abavela eSikoleni Sekhemisi saseZHONGSHAN University lashicilela iphepha ku-ARCHIVES OF TOXICOLOGY, iphephabhuku eliyinhloko le-global toxicology, libonisa ukuthi ngethamo elifanayo le-nicotine, i-e-cigarette sol ayinabungozi kangako ekuphefumuleni. uhlelo kunogwayibhema.

Eminyakeni yamuva nje, imiphumela yezempilo ye-e-cigarettes nogwayi iye yaphikisana kakhulu emkhakheni wezempilo yomphakathi.Kulolu cwaningo, ithimba labacwaningi beNyuvesi yase-ZHONGSHAN liqhathanise imiphumela kagwayi kanye ne-e-cigarette ekusebenzeni kwamaphaphu, izici ezivuthayo kanye nokubonakaliswa kwamaprotheni kumagundane anokuqukethwe okufanayo kwe-nicotine, okugcwalise igebe locwaningo lwesayensi emikhakheni ehlobene.

Abacwaningi basebenzisa ikhabe le-RELXugwayi we-e enongiwekanye nogwayi wendabuko njengamasampula, isamba samagundane we-32 ahlukaniswe ngokungahleliwe abe ngamaqembu e-4 futhi avezwe emoyeni ohlanzekile, umthamo ophansi we-e-cigarette sol, umthamo omkhulu we-e-cigarette sol kanye nomusi kagwayi amasonto e-10, futhi izinkomba zabo zahlaziywa.

Imiphumela ye-histopathology yamaphaphu yabonisa ukuthi i-coefficient yamaphaphu achayeke kugwayi anda kakhulu, futhi nendlela yokuma kuqhoqhoqho yashintsha, okusikisela ukuthi isimiso sokuphefumula singase sibe nesifo.Uma kuqhathaniswa, alukho ushintsho oluphawulekayo ku-coefficient yamaphaphu kanye ne-trachea morphology kumagundane achayeke ku-e-cigarettes.

Ukuhlolwa kokusebenza kwamaphaphu kubonise ukuthi ukuchayeka kukagwayi kubangele ukungahambi kahle okuphawulekayo enanini lezinkomba zokusebenza kwamaphaphu kumagundane, kodwa inkomba eyodwa kuphela eyehlile eqenjini le-e-cigarette.Ngesikhathi esifanayo, imiphumela ye-pathological yabonisa ukuthi kokubili ugwayi kanye ne-e-cigarette kungase kubangele ukuphazamiseka kwamaphaphu kumagundane, kodwa umonakalo obangelwa ugwayi wawusobala kakhulu.

Ekugcineni, umcwaningi uphinde wenza ukuhlaziywa kwe-proteomic kwezicubu zamaphaphu egundane.Imiphumela yabonisa ukuthi izinguquko zamaprotheni ezihlukene ezibangelwa ugwayi zazigxile kakhulu izindlela ezihlobene nokuvuvukala, kuyilapho inkulumo engavamile ebangelwa i-e cigarette yayincane, futhi umphumela endleleni yokubonisa ukuvuvukala yayincane.

Abacwaningi bathi imiphumela ikhombisa ngokusobala ukuthi ukuchayeka kumithamo emikhulu kagwayi kanye nogwayi we-e kuyingozi ohlelweni lokuphefumula.Kodwa-ke, ngaphansi kwe-nicotine efanayo, i-e-cigarette sol ayinabungozi kangako ohlelweni lokuphefumula kunentuthu kagwayi wendabuko.

I-vaping ibonwa kabanzi umphakathi wezokwelapha njengenye indlela engenabungozi ngoba ayikhiqizi itiyela futhi ayidingi ukushiswa.